Thursday, November 28, 2019

College Technology Admission essay

Since childhood, I have been interested in the exquisite design rides for the Walt Disney Company. My interest in advancing my fascination for design rides into a career stems from my grandmother’s influence who introduced me into the Disney world at the age of two. Advertising We will write a custom essay sample on College Technology Admission essay specifically for you for only $16.05 $11/page Learn More I grew up in New York and moved to the state of Florida in 2006. Before my grandmother passed on in 2004, she took me to Disney world every year during my vacations and the great experience I earned has always stirred my interest to want to associate with them. My favourite subjects are mathematics and science. I believe through the study of design rides, I will satisfy my curiosity to join Walt Disney Company. Through the study of design rides, I will have the opportunity to serve my country. I will blend my good analytical skill with the knowl edge acquired in school to design and build unique Disney theme parks and other venues of entertainment at various levels of development. My interest in computer and video games improves my imagination, giving me a wild array of the imaginary world. In the summer of 2011, I attended a technology seminar at Stanford University with People to People Organization. The opportunity to participate in this seminar gave me an avenue to learn technology and other related issues in the Apple Company. My interest in technology comes from the desire to social advancement. The world is going hi-tech and sooner or later, technology is bound to rule the society (Myers 19). My interest in technology from childhood makes it easier for me to adapt to changes, analyse events and map the associated ideas in an extraordinary way. When my parents noticed that I had undying interest in technology, they started introducing me to programs related to technology early in life. My excellent performance in the fields of mathematics and science has convinced them that my dreams are achievable. My father has supported me through encouraging me to attend seminars and computer classes to get accustomed with the practice of technology in various companies. I believe that my endeavour to pursue issues related to technology has enhanced my writing, reading and mathematics skills and this is evident through my exemplary performance. Currently, I’m in a computer academy taking Microsoft classes to gain knowledge and obtain Microsoft certifications. The fast development of technology has pushed humanity to a new era whereby people are expected to perform less physical work and improve on their mental work to attain the required results (Myers 34). Advertising Looking for essay on computer science? Let's see if we can help you! Get your first paper with 15% OFF Learn More Technology improves communication and enables people to expand on their intellectual potential. Through th e training on technology, sharing experiences with people from the corporate world and observation in various firms, I have understood the advantages and limitations of technology, I have learned how to use computers and its associated software and I have grown to appreciate the effect of technology in the society. The rate of assimilation of technology has been stalled by the complexity of its use. However, the striking designs of the Disney world are enough to make me go out of my way to acquire what it takes to fit into their team. This is because I also want to give someone else the good experience I got from spending my vacations at the Disney world. I hope to continue developing my technology knowledge and skills in your institution. Work Cited Myers,Sarah. The College Application Essay: The College Board. New York: Prentice Hall, 2012. This essay on College Technology Admission essay was written and submitted by user Braylin Jefferson to help you with your own studies. You are free to use it for research and reference purposes in order to write your own paper; however, you must cite it accordingly. You can donate your paper here.

Monday, November 25, 2019

Hobbes vs. Locke essays

Hobbes vs. Locke essays Who do you agree with, Locke or Hobbes, and why? I believe that Hobbes is genuinely correct in stating that man is greedy and ambitious in nature. Most things revolve around money and power, therefore profit motif serves as the force that drives us. We constantly try excel in everything and thus compete with ourselves and with our neighbors. I do believe that everything we do is driven by one of two ways Hobbes mentions: self interest. Realistically, even the most charitable gesture is ultimately self-serving. Still when we do noble deeds, we feel good about ourselves; about something meant for another but born in me and that leads to pride and high self esteem. It is no sin to feel good about something, but it is no lie that even when a noble cause is completed, we are filled with a different sensation we lacked beforehand. Notwithstanding, I agree with Lockes ideas on how a man is corrupted with the creation of properties and the acquired value of natural resources. I am not completely certain that men rob others from their natural born right to own what Nature has offered, but in accordance to Locke, I disagree with men hoarding more than they can make use for. Ultimately, men need Nature or each other, therefore I concur with Locke when he sets an example placing a man, with abundant resources he has labored and are thus his, in the middle of nowhere who will eventually give in to Nature or another human because he has no use for his excise. ...

Thursday, November 21, 2019

Summery Essay Example | Topics and Well Written Essays - 500 words

Summery - Essay Example (Richardson) Most of the people believe that teachers are reluctant in implementing changes in their teaching strategies because they feel threatened, defensive, and perhaps rushed when somebody demands change in their methods. In fact teachers undertake change voluntarily, following their sense of what their students need and what is working. Voluntary change is what teachers actually do in their classrooms; it does not necessarily lead to exemplary teaching (Richardson) The induction teacher’s and experienced teacher’s approach to the change management may be different. The induction teachers experienced more change in their beliefs than their practices, whereas experienced teachers demonstrated more change in their practices than their beliefs. (Luft,p. 531) The experienced teachers always have a strong belief in the traditional methods of teaching; but they were forced to change their practices because of the external pressure from the authorities. On the other hand, the induction teachers may not have much practical experiences and their beliefs also may not be adequate. So they will be more flexible as far as change in beliefs is concerned. â€Å"If all teachers make decisions autonomously, the schooling of an individual student could be quite incoherent and ineffective. This, too, suggests that help, direction, or encouragement provided to staff rather than to individuals could be necessary to promote change that is valuable to the learner† (Richardson) Beliefs are critical when it comes to understanding a teacher’s practice. For example, two mathematics teachers with similar knowledge may taught in different ways. Understanding of beliefs was more useful in predicting teachers’ classroom decisions (Luft & Roehrig p.40) Institutions cannot behave like a market place where all the deals were based on competitions and bargaining. It should be functioned in a

Wednesday, November 20, 2019

Biology Research Essay Example | Topics and Well Written Essays - 1500 words

Biology Research - Essay Example Basal like tumors are most commonly found in Nigeria and Senegal. Research is on to find drugs to block the specific molecules that these tumors need to grow. Women with mutations in a gene called Brca1 tend to develop this kind of aggressive breast tumor. Patterns of genetic activity of these tumors are measured through special tests because what the biological tests reveal turn out to be quite different from what the human eyes perceive. Researchers used new techniques of molecular biology to determine the patterns of gene activity in the cancer cells and then to classify and sort the subtypes by race. Further research is on to find an alternative to chemotherapy. Women of race are advised to get counseling in preventive care well before 40 especially if it runs in their family. As the incidence of breast cancer and mortality due to breast cancer keeps increasing in the USA, researchers and oncologists have been intrigued trying to find the root cause of breast cancer. While various physiological reasons have been associated, recent findings suggest that environmental factors react with genetic and individual predisposing factors and cause malignant tumors to develop in breast tissue. A paper Breast cancer and environmental risks: where is the link? by Mitra et al., (2004) was published in Journal of Environmental Health. To asses the environmental agents, the authors have reviewed previous studies focusing on xenoestrogens, organochlorines, polychlorinated biphenyls, and other environmental agents. Results revealed that exogenous estrogens present in the environment increase the growth of breast cancer cells while hormone replacement therapy (HRT) and oral contraceptives also play a significant role in the development of breast cancer during adolescence. X enoestrogens may increase the risk of cancer among those who are

Monday, November 18, 2019

Adolescent Suicide Research Paper Example | Topics and Well Written Essays - 2000 words

Adolescent Suicide - Research Paper Example Even silly problems will be perceived as complicated ones and they may take decision to commit suicide to escape from such problems. In many cases, substance abuse, momentary lapse of emotional control, lack of counseling, negligence from parents and beloved ones, stressful events are motivating teenagers to commit suicide. Teenagers with family history of suicide show more tendencies to commit suicide. Nursing professionals can help teenage community immensely in preventing suicide. They can help teenagers to solve their physical as well as mental problems with the help of proper medications and counseling. This paper analyses the reasons of teenage suicide and the nursing implications with respect to this social problem. Adolescent Suicide Suicide is the third leading cause of death in 15 to 24 year olds, and the third leading cause of death in 10 to 14 year olds. According to the National Institute of Mental Health (NIMH): There are 25 attempted suicides to one completed suicide - with the ratio even higher in youth and the strongest risk factors for attempted suicide in youth are depression, substance abuse, and aggressive or disruptive behaviors (Teen Suicide, n.d). It is impossible to know the teenager who committed suicide first in this world. It is also impossible to predict who could be the last teenager to commit suicide. ... Although child death rates are decreasing steadily during the last few decades, youth suicide rate travels in the opposite direction in United Sates. Reasons for adolescent suicide and nursing implications According to Shilubane et al. (2012), â€Å"Lack of knowledge of available counselors, conflicts in interpersonal relationships, perceived accusations of negative behavior, inadequate social support, past family and peer suicide attempts and poor living circumstances were factors found to be related with suicide attempts† (Shilubane et al. 2012, p.177). As mentioned earlier, many teenagers are committing suicide because of a momentary lapse in emotional control. For example, love affairs or dating relationships are common among current teenagers all over the world and the case of America is also not an exception. Teenagers who have feeble mental power or self-confidence may think about committing suicide when their love affairs break. They may not bother too much to think ab out substituting the lost relationships with another one at that moment. For them breaking of their dating relationships is the end of the road. Nursing professionals can help teenagers to overcome the emotional catharsis at various moments in their life. Many studies have proved beyond doubt that lack of availability and access to counseling is the major reason for increased suicide rates among teenagers. Counseling should be done at individual levels and family levels to educate the public about how to overcome stressful events and avoid suicides. Family nurse practitioner (FNP) is a respected profession in America now and these professionals can help the community in general and teenage community in particular in overcoming the tendencies of suicide. Poor living condition is

Saturday, November 16, 2019

Enzyme Kinetics Laboratory Report

Enzyme Kinetics Laboratory Report How the changes in substrate concentration (PNPP), changes in temperature, changes in pH and the presence of an inhibitor (phosphate ions) effects the rate of reaction of the reaction between PNPP and water catalysed by the enzyme acid phosphates which produces PNP and phosphate as its products . Using spectrophotometer to measure the absorbance of the products formed through hydrolysis of substrate. Abstract: The purpose of this scientific paper was to replicate earlier findings of experiments in enzyme kinetics and to see if enzyme behaviour and activity is influenced by 4 factors- change in substrate concentration, temperature, pH and the presence of a competitive inhibitor. In the first section where the substrate concentration was altered whilst the enzyme concentration was kept constant the relationship was found to be hyperbolic this can be explained using the Michaelis -Menten equation and the Lineweaver burk plot which was also used to obtain Km values of 0.25 and Vmax values of 0.12UNIT. The increase in [S] increased the rate of reaction at first but when [S] too much the initial velocity started to decrease. The increase in temperature led to a general increase in the initial velocity until the temperature reached 347 K where the enzyme denatured. The optimum temperature of the reaction was in the range 310 K- 323.2 where the rate increased at its fastest. The third section was the effect of pH on the enzyme activity. The optimum pH of the reaction was 5.5. This pH gave the highest reading of absorbance which means that the rate of hydrolysis was at its highest. Finally the last section of the experiment was the effect of competitive inhibitor on the rate of reaction. The investigation showed that the inhibitor used (phosphate ions) was a non-competitive inhibitor. The inhibitor did lower the initial velocity of the reaction when it attached to the enzyme at random. Introduction: This laboratory report is on the topic of enzyme kinetics, previous work in this particular field was carried out in the 1700s, when biological catalyst enzymes were discovered and studied. As understanding of enzymes increased scientist carried out basic laboratory experiments such as the conversion of starch to sugar by saliva to increase their understating of enzymes and how they function. However the first actual incident where enzymes were understood in detail was in 1897-by Edward Buchner .Since then on, till this period of time factors which effect the velocity/ rate of reaction and enzymes have been studied widely by many scientists globally. The modern scientists have a deep understanding of enzyme kinetics. The purpose of this laboratory report is to confirm previous findings covered in various sources of scientific literature and journals. Enzymes are often described as organic catalysts which increase the rate of reaction of a bio-chemical reaction ( David L.Nelson etal 2008). Enzymes increase the rate velocity of various reactions that occur in a biological system such as the mammalian digestive system. Enzymes can have functions including transfer, synthesis or breakdown of molecules. It is important to mention that enzymes are proteins which speed up the rate of reaction without being used up themselves i.e. they are reusable. Enzymes have a very specific active site which is complementary to a specific substrate 3 dimensional structure. The specificity is due to the complementary hydrophilic/hydrophobic charge, electrical charge and shape of active site on the enzyme. The binding of an enzyme with an specific substrate produces an enzyme substrate complex (ES).The rate at which the enzyme substrate complex is formed is dramatically increased or decreased in changes in substrate concentration, temperature, pH and presence of an competitive inhibitor the effect of these 4 factors on the enzyme activity is known as enzyme kinetics (Jeremy M. Berg etal 2006).Enzymes work on the concept of transition states. Transition state of enzymes is the phase where the substrate is not a yet a product and not a substrate. Enzymes reduce this phase .The difference between the free energy of the reactants and the free energy of the transition state is the activation energy (Ea).The minimum energy required for a success full reaction to occur. Enzymes speed up the rate of reaction by lowering the activation energy barrier. A typical enzyme substrate reaction can be simplified and be written as: The enzyme studied in this investigation was acid phosphatase. This enzyme can be identified by its Enzyme Commission Number (EC number) which is 3.1.3.2. Now I will briefly discuss the enzyme kinetic properties of acid phosphatase. The enzyme acid phosphatase catalyses the removal of phosphate group from organic molecules. Its primary mechanism of action is to bring a substrate molecule into contact with a molecule of water .This results in catalysis and the removal of phosphate group. Finally an hydroxyl group is attached to the substrate molecule. An example of this is the reaction shown below. This reaction was studied in this laboratory investigation. Acid phosphatase p-nitrophenylphosphate (PNPP) + water phosphate + p-nitrophenol(PNP) In the reaction above PNPP is the synthetic substrate, which is described as chromogenic.At. At high purity this compound is completely colourless. PNPP is hydrolysed by the enzyme acid phosphatase this produces phosphate and PNP. The product produced is yellow and can be measured using a colorimeter. The first part of the investigation concerns the effect of substrate concentration on the rate of reaction. I predict and expect that at an increase in substrate concentration (PNPP) will lead to an increased rate if reaction/initial rate. The reason for this is that an increase in substrate concentration increases the chances of a successful collision occurring between the enzyme and substrate increasing the likelihood of ES complex and product (PNP) formation results in an overall increase rate of reaction. This will produce a fist order reaction on a graph. However it is important to mention that at high substrate concentration the enzyme will be fully saturated this will reduce the rate of reaction as the there are too many substrate than enzymes. On a graph this would show a plateau. The maximum velocity of the reaction or the Vmax would be expected to be close to this region. Therefore I predict to see a hyperbolic relationship on a graph. Section B of this investigation concerns the effect of temperature on the rate of reaction. I would exepcet to find that an increase in temperature would result in an increase in the rate of reaction. The reason for this phenomenon is that as there is increase in kinetic energy being applied to enzymes and substrates it increases the chances of collision occurring so more product (PNP) is formed per unit time. However I also believe that temperatures above 50 -70 degrees Celsius would denature the enzymes active site and the 3 dimensional structures. At this stage the enzyme will not be complementary in shape to the substrate. This would mean that no reaction can be completed so the rate of reaction will decrease. It is important to state that the enzyme is going to have an optimum temperature at which the ES complexes and products are made at the fastest velocity. The increase in temperature increase the amount of molecules which have higher energy than the Ea barrier this in turn increases the amount of molecules which can react increasing the rate of reaction or initial velocity. I believe the optimum temperature is going to range between 20-40 degrees Celsius. The third part of this lab report is based on the effect of pH on the rate of reaction again I believe that at extremes of pH such as acidity or alkalinity will affect the rate of reaction. This may cause the enzymes structure to denature and will cause a lower rate of reaction and lower rate of product formation because the enzyme will not be complementary to the substrate. I would expect this enzyme to have a low optimum pH of around 5-2 as it is acid. Finally the last section of this investigation concerns the effect of a competitive inhibitor (phosphate ions) on the rate of reaction. Inhibitor in this case the phosphate ions will compete with the actual substrate PNPP for the active site of the enzyme acid phosphatase. These inhibitors can only attach to the active site of the enzyme due to their complementary properties. The concentration of the inhibitors will be kept constant and the concentration of the substrate PNPP will be altered. I believe that as the concentration of PNPP increases the rate of reaction will increase this is because the PNPP can out- compete the competitive inhibitor and reverse the effect of the inhibitor. Materials and Methods: All procedures were carried out as described in the lab schedule. No alterations were made to any of the procedures carried out throughout the experiment. Discussion: The first section of this lab report relates the effect of substrate concentration on enzyme activity. I shall briefly discuss and explain what my data shows and means. Graph 3 which is the graph of Michaelis Menten of collected data. The relationship between the rate of an enzyme-catalysed reaction and the substrate concentration can be describes as hyperbolic. The graph and tables 2 show that as the concentration of substrate (PNPP) increases from 0.00 Mmols to 0.20 Mmols of substrate the initial velocity or the rate of reaction shows an increase in too. The relationship can be describes as fist order as the [V] rises almost linearly with the increase in [S]. However after the concentration increase from 0.20- to 3.00 Mmols the initial velocity shows a gradual increase and then gradually levels of or slopes here graph shows 0 order relationship. This supports the prediction I made in the introduction. The graphs indicates that as the concentration of substrate increase the rate of reaction increase this is because of the increase chances of a collision between a substrate and an enzyme. This in turn increases the rate at which ES and P are formed. However after the concentration increase after 0.20 3.00 Mmols the rate stars to level off. The reasoning behind is this is that there are too many substrates than compared to enzymes an all enzymes are described to be fully saturated .At this phase the reaction is at its Maximum velocity and cannot increase in rate unless more enzymes are added therefore enzyme concentration is the limiting factor. I can tell that the data I collected from the experiment in the lab is accurate and valid as the graph which compares the theatrical data and the collected data show similarities in the trend line the Vmax the km and as well as the points and there is no anomalous data point on either of the 3 graphs. My findings support the findings of many previous investigations and journals as the graphs show a similar relationship as to the findings to previous work. The implications of this investigation can be used widely to determine the Vmax and KM. These values can be used for medical purposes since the enzyme acid phosphatase is manufactured by the body to remove phosphate groups. The limitation of Michaels Menten plot is that the Km and Vmax cannot be accurately determined. Therefore a Lineweaver burk plot is plotted. The Lineweaver burk plot shows that the KM and Vmax are very similar to the ones from the Michaelis Menten plot. Finally KM is an approximate measure of the affinity of an enzyme for its substrate.A small value of KM indicates a high affinity of the enzyme for the substrate. From my graphs (1 +2) I can tell that the KM was 0.24 and therefore small. This means that the enzyme acid phosphatase has a high affinity for the synaesthetic substrate PNPP. This means that small concentration of substrate PNPP is enough to run the reaction at half of maximum velocity (1/2 Vmax). The next section of the investigation concerns the effect of temperature on the rate of reaction. I predicted an increase in temperature will increase the rate of reaction or the initial velocity of the e reaction until the enzyme denatures and the protein sequence becomes damaged an unravels. The actual reason for why the protein sequences unravel is that the protein has too much kinetic energy and the amino acids vibrate and this causes the non covalent forces to be weakened. There is an increase in the rate of reaction as the temperature increases from 278 -323 K the increase is almost linear. However after the temperature 323 K-to 347 K the enzyme denatures and unravels. This is proved by the last point on the graph which doesnt fit the line of best fit. Overall the graphs and data all prove my predictions correct. There is no other anomalous data present. The third section concerns the effect of pH on the rate of reaction. As we have discovered before the enzyme used was acid phosphatase so the pH at which it works at best the optimum temperature will be in the acidic pH regions. I can confirm from my graph that the optimum pH of the reaction is in the region 5-5.5 which is indeed acidic. pH of 5.5 gives the highest absorption value, this therefore means that the rate of hydrolysis was at its fastest. A possible explanation for the change in the experimental design is that the pH may denature the enzyme if the enzyme was added first the active site and 3 dimensional shape of the enzyme could be altered at extremes of pH such as 2 which is quite acidic. The pH does not affect the substrates 3 dimensional structure in the same ways as the enzymes. Therefore to obtain valid results /data the design for this part of the experiment was slightly altered. pH has a very strong effect on enzyme activity .This is because enzymes work on the basis of mechanisms such as induced fit hypothesis and lock and key . The enzymes have a specific active site due to the complementary 3 dimensional active site with the substrate. According to the induced fit hypothesis the enzyme can undergo some change in the 3- dimensional structure in order to fit the substrate. However a change in pH changes the enzymes active site structure. An increase in H+ ions can change the active site structure due to the fact that h+ ions can interfere with any polar molecules on enzymes protein structure. Amino acids side chains can be protonated and may be damaged due to the extreme pH (concentration of H+ )this may result in the protein sequence to unravel which means that the active site is not complementary to the substrate and the rate of reaction decreases as no or little ES are formed which results in little products formed. The final section concerns the effect of a competitive inhibitor (phosphate ions) on the rate of reaction. From my graph I can tell that the inhibitor present was an non-competitive inhibitor. I can tell this by looking at the Lineweaver Burk plot where the trend lines cross the 1/Vmax intercept at different values but cross the 1/km intercept at the same values. This means that this type of inhibitor does not affect the KM but does lower the Vmax values. Non competitive inhibitor has the same effect as lowering the total volume of enzyme. This type of inhibition is reversible. It binds to a site away from the enzymes active site it denatures the active site so no other substrates can bind to the active site. This in turn lowers the rate of reaction and the rate at which products are formed. However this type of inhibitor also binds to the enzyme substrate complex I can therefore conclude that the non competitive inhibitor does lower the rate at which the products are formed. References: Books: David L. Nelson et al (2008) Lehninger Principles of Biochemistry ,W.H Freeman and Company Jeremy M. Berg et al (2006) Biochemistry, W.H Freeman and Company Lab schedule (2009) Enzyme Kinetics MODULE LSC10034 EXPERIMENT 4 Lecture Notes: Lectures notes (2009) Dr John Mills- Module LSC-10034 Proteins and Enzymes lectures 9, 10, 11 (Figures 1-5) Absorbance values- Table 4 and Table 6 Emma Ezekiel Web Pages: EC Number -http://www.brenda-enzymes.org/php/result_flat.php4?ecno=3.1.3.2 Seen :20 November 2009

Wednesday, November 13, 2019

Comparing Mans Downfall in Second Coming and The world is too much wit

Man's Downfall in Second Coming and The world is too much with us  Ã‚     Ã‚   Although W.B. Yeats wrote roughly a century after the Era of Romanticism, his Romantic precursors influenced his writing greatly. One of his most famous poems, "The Second Coming," echoes both Blake's The Book of Urizen and Shelley's most ambitious poem Prometheus Unbound (Bloom 530). Despite less criticism on the relationship between Yeats's poems and the writing of another one of his Romantic predecessors, William Wordsworth, Wordsworth's reproach of greed and materialism in a waxing industrial society influences Yeats' poetic interpretation of the apocalypse. Both Wordsworth and Yeats depict man's downfall; "The world is too much with us" foreshadows and describes the reasons for the predicted apocalypse of The Second Coming. A cultural concentration on redundant commercialism, loss of focus on nature, and lack of conviction fuel both poems, yet only Yeats envisions the graphic result in an eventual takeover of man. In the first four lines of "The world is too much with us," the speaker laments man's shift of focus from nature to materialism: The world is too much with us; late and soon, Getting and spending, we lay waste our powers: Little we see in Nature that is ours; We have given our hearts away, a sordid boon (Wordsworth 1394)! Wordsworth, normally writing in a much softer tone indicative of the Romantic style which he helped to define, begins the sonnet with a strong, scolding voice associated so specifically with Milton (Levinson 644). He emphatically condemns the "vulgar materialism" of the age exhibiting the human race's frivolousness and frets that instead of looking to Nature (their own and the surrounding), human... ... Cantor, Jay. "History in the Revolutionary Movement: Men Made Out of Words." The Space Between: Literature and Politics. Johns Hopkins University Press, 1981. Rpt. in Twentieth-Century Literary Criticism. Ed. Dennis Poupard. Vol. 11. Detroit: Gale, 1983. 540-541. Levinson, Marjorie. "Back to the Future: Wordsworth's New Historicism." South Atlantic Quarterly 88 (1989): 633-659. Profitt, Edward. "Yeats's 'The Second Coming.'" Explicator 49 (1991): 104-105. Wordsworth, William. "The world is too much with us." The Norton Anthology of English Literature. 6th ed., the major authors. Ed. M. H. Abrams. New York: W.W. Norton and Company, Inc., 1996. 1394. Yeats, William Butler. "The Second Coming." The Norton Anthology of English Literature. 6th ed., the major authors. Ed. M. H. Abrams. New York: W.W. Norton and Company, Inc., 1996. 2280    Â